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File:How random DNA libraries sample sequence space.pdf

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    English: Depiction of how DNA libraries created by random diversity-generation techniques sample the sequence space. The amino acid substituted into a given position is shown. Each dot or set of connected dots is one member of the library. Error-prone PCR randomly mutates some residues to other amino acids. Alanine scanning replaces each reside of the protein with alanine, one-by-one. Site saturation substitutes each of the 20 possible amino acids (or some subset of them) at a single position, one-by-one.
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    Author Rob Hurt

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    DNA libraries created by random diversity-generation techniques

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    sequence space

    inception

    3 April 2020

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