Genomes don't just encode protein-coding RNAs. They also give rise to various groups of RNAs that can regulate gene expression. Short RNAs that form from enhancer sequences might be one such class of regulatory RNA.
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References
Maston, G. A., Evans, S. K. & Green, M. R. Annu. Rev. Genom. Hum. Genet. 7, 29–59 (2006).
Visel, A., Rubin, E. M. & Pennacchio, L. A. Nature 461, 199–205 (2009).
Heintzman, N. D. et al. Nature 459, 108–112 (2009).
Kim, T.-K. et al. Nature 465, 182–187 (2010).
Heintzman, N. D. & Ren, B. Curr. Opin. Genet. Dev. 19, 541–549 (2009).
Koch, F., Jourquin, F., Ferrier, P. & Andrau, J.-C. Trends Biochem. Sci. 33, 265–273 (2008).
Kapranov, P., Willingham, A. T. & Gingeras, T. R. Nature Rev. Genet. 8, 413–423 (2007).
Ling, J. et al. J. Biol. Chem. 279, 51704–51713 (2004).
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Ren, B. Enhancers make non-coding RNA. Nature 465, 173–174 (2010). https://doi.org/10.1038/465173a
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DOI: https://doi.org/10.1038/465173a