File:Two steps in Cdk activation.pdf
Size of the above preview of this PDF file: 960 × 533 pixels. Other resolutions: 330 × 183 pixels | 1,280 × 711 pixels | 1,920 × 1,067 pixels.
Original file (2,700 × 1,500 pixels, file size: 1.18 MB, MIME type: application/pdf)
Captions
Captions
Two steps in Cdk activation
Summary
[edit]| Description |
English: Cyclin binding alone causes partial activation of Cdks, but complete activation also requires activating phosphorylation by CAK. In animal cells, CAK phosphorylates the Cdk subunit only after cyclin binding, and so the two steps in Cdk activation are usually ordered as shown here, with cyclin binding occurring first. Budding yeast contains a different version of CAK that can phosphorylate the Cdk even in the absence of cyclin, and so the two activation steps can occur in either order. In all cases, CAK tends to be in constant excess in the cell, so that cyclin binding is the rate-limiting step in Cdk activation.[1] |
| Date | |
| Source | The Cell Cycle. Principles of Control. |
| Author | David O Morgan |
Licensing
[edit]
|
The copyright holder of this file allows anyone to use it for any purpose, provided that the copyright holder is properly attributed. Redistribution, derivative work, commercial use, and all other use is permitted. |
|
|
File history
Click on a date/time to view the file as it appeared at that time.
| Date/Time | Thumbnail | Dimensions | User | Comment | |
|---|---|---|---|---|---|
| current | 02:12, 8 April 2020 |  | 2,700 × 1,500 (1.18 MB) | Rob Hurt (talk | contribs) | Uploaded a work by David O Morgan from The Cell Cycle. Principles of Control. with UploadWizard |
You cannot overwrite this file.
File usage on Commons
There are no pages that use this file.
File usage on other wikis
The following other wikis use this file:
- Usage on el.wikipedia.org
- Usage on en.wikipedia.org
